AQP0 antibody, CTRCT15 antibody, LIM1 antibody, MIP26 antibody, MP26 antibody, Aqp0 antibody, Cat antibody, Hfi antibody, Lop antibody, Svl antibody, shrivelled antibody, MP22 antibody, aqp0 antibody, lim1 antibody, mp26 antibody, mip26 antibody, MIP antibody, mip1 antibody, zgc:100858 antibody, mip2 antibody, zgc:110015 antibody, major intrinsic protein of lens fiber antibody, major intrinsic protein of lens fiber L homeolog antibody, major intrinsic protein of lens fiber a antibody, major intrinsic protein of lens fiber b antibody, MIP antibody, Mip antibody, mip.L antibody, mip antibody, mipa antibody, mipb antibody
背景
Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80 % of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains.