8030469P05 antibody, C530050O22Rik antibody, ENSMUSG00000070923 antibody, mKIAA1354 antibody, RGD1304814 antibody, kelch-like 9 antibody, kelch-like family member 9 antibody, kelch like family member 9 antibody, Klhl9 antibody, KLHL9 antibody
背景
This gene encodes a protein that belongs to the kelch repeat-containing family, and contains an N-terminal BTB/POZ domain, a BACK domain and six C-terminal kelch repeats. The encoded protein is a component of a complex with cullin 3-based E3 ligase, which plays a role in mitosis. This protein complex is a cell cycle regulator, and functions in the organization and integrity of the spindle midzone in anaphase and the completion of cytokinesis. The complex is required for the removal of the chromosomal passenger protein aurora B from mitotic chromosomes.