IL34
适用: 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
应用备注
IHC/IF (M,R) 1:500-1:1500
限制
仅限研究用
状态
Liquid
缓冲液
PBS, pH 7.4, 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
抗原
IL-34 (IL34)
(Interleukin 34 (IL34))
别名
IL-34
背景
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.