ri58 antibody, DKFZp469M2320 antibody, P58 antibody, RI58 antibody, interferon induced protein with tetratricopeptide repeats 5 antibody, interferon induced protein with tetratricopeptide repeats 5 L homeolog antibody, interferon-induced protein with tetratricopeptide repeats 5 antibody, IFIT5 antibody, ifit5.L antibody, LOC100024963 antibody, LOC100151816 antibody, ifit5 antibody
背景
Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.