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CD51 抗体

ITGAV 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074314
发货至: 中国
  • 抗原 See all CD51 (ITGAV) 抗体
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    适用
    • 93
    • 51
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    人, 小鼠, 大鼠
    宿主
    • 64
    • 30
    • 9
    克隆类型
    • 57
    • 45
    多克隆
    标记
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    This CD51 antibody is un-conjugated
    应用范围
    • 48
    • 46
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
    Top Product
    Discover our top product ITGAV Primary Antibody
  • 应用备注
    IHC/IF (H,M,R) 1:500-1:2000/1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    别名
    Integrin alpha V (ITGAV 产品)
    别名
    1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
    背景
    The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
    基因ID
    16410
    NCBI登录号
    NP_032428
    UniProt
    P43406
    途径
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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