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ISR-alpha 抗体

ISR-alpha 适用: 人, 大鼠, 小鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074298
发货至: 中国
  • 抗原 See all ISR-alpha 抗体
    ISR-alpha (Insulin Receptor alpha (ISR-alpha))
    适用
    • 52
    • 41
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 45
    • 7
    克隆类型
    • 33
    • 16
    • 3
    多克隆
    标记
    • 14
    • 3
    • 2
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    • 2
    • 2
    • 2
    • 2
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    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This ISR-alpha antibody is un-conjugated
    应用范围
    • 27
    • 26
    • 19
    • 15
    • 12
    • 11
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse Insulin Receptor alpha
  • 应用备注
    IHC: 1: 3000-1: 6000
    Human, Mouse, Rat: Human, Mouse, Rat
    Positive Tissue: endometrial cancer, esophagus cancer, uterus,small intestine
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ISR-alpha (Insulin Receptor alpha (ISR-alpha))
    别名
    Insulin Receptor alpha (ISR-alpha 产品)
    别名
    CD220 antibody, HHF5 antibody, insulin receptor antibody, INSR antibody
    背景
    This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
    基因ID
    16337
    UniProt
    P15208
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