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CD74 抗体

CD74 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074245
发货至: 中国
  • 抗原 See all CD74 抗体
    CD74 (HLA-DR-gamma (CD74))
    适用
    • 185
    • 65
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    小鼠, 大鼠
    宿主
    • 118
    • 86
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    克隆类型
    • 132
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    多克隆
    标记
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    This CD74 antibody is un-conjugated
    应用范围
    • 121
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    Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse CD74
    Top Product
    Discover our top product CD74 Primary Antibody
  • 应用备注
    IHC/IF (M,R) 1:1000-1:4000/1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    CD74 (HLA-DR-gamma (CD74))
    别名
    CD74 (CD74 产品)
    别名
    DHLAG antibody, HLADG antibody, II antibody, Ia-GAMMA antibody, CLIP antibody, Ii antibody, INVG34 antibody, Iclp-1 antibody, iclp1 antibody, wu:fb11f09 antibody, wu:fb12a01 antibody, wu:fb13d06 antibody, wu:fk94e07 antibody, Iclp-2 antibody, cd74 antibody, iclp2 antibody, zgc:123161 antibody, CD74 molecule antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 molecule, major histocompatibility complex, class II invariant chain a antibody, CD74 molecule, major histocompatibility complex, class II invariant chain b antibody, CD74 antibody, Cd74 antibody, cd74a antibody, cd74b antibody
    背景
    CD74, also known as the MHC class II associated invariant chain (Ii), is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is produced in molar excess over MHC class II and some of this is expressed by an unknown pathway on the cell surface independent of or in association with MHC class II molecules. The half life of CD74 on the cell surface is only 3 to 4 min after which it is internalized.
    基因ID
    16149
    NCBI登录号
    NP_001036070
    UniProt
    P04441
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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