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GBA 抗体

GBA 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7074062
发货至: 中国
  • 抗原 See all GBA 抗体
    GBA (Glucosidase, Beta, Acid (GBA))
    适用
    • 52
    • 28
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 62
    • 10
    克隆类型
    • 56
    • 16
    多克隆
    标记
    • 31
    • 15
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GBA antibody is un-conjugated
    应用范围
    • 52
    • 25
    • 24
    • 8
    • 8
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse GBA
    Top Product
    Discover our top product GBA Primary Antibody
  • 应用备注
    IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    GBA (Glucosidase, Beta, Acid (GBA))
    别名
    GBA (GBA 产品)
    别名
    GBA1 antibody, GCB antibody, GLUC antibody, BETA-GLUCOSIDASE antibody, T12J13.8 antibody, T12J13_8 antibody, beta glucosidase 25 antibody, PSPTO3318 antibody, PSPTO4290 antibody, GC antibody, GCase antibody, betaGC antibody, glucosylceramidase beta antibody, beta glucosidase 25 antibody, beta-glucosidase antibody, Beta-glucosidase antibody, glucosidase, beta, acid antibody, glucosylceramidase antibody, bglX-2 antibody, GBA antibody, BGLU25 antibody, PSPTO_3318 antibody, bglX antibody, bglA4 antibody, Gba antibody, LOC100399524 antibody, bglA.2 antibody, bglX-2 antibody
    背景
    The GBA is a glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes . Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism . May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol . The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol .
    基因ID
    14466
    NCBI登录号
    NP_001070879
    UniProt
    P17439
    途径
    Cellular Glucan Metabolic Process
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