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CUBN 抗体

CUBN 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7073601
发货至: 中国
  • 抗原 See all CUBN 抗体
    CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
    适用
    人, 大鼠, 小鼠
    宿主
    • 49
    • 1
    克隆类型
    • 41
    • 9
    多克隆
    标记
    • 12
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CUBN antibody is un-conjugated
    应用范围
    • 21
    • 15
    • 13
    • 13
    • 8
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein corresponding to Mouse Cubilin
  • 应用备注
    WB (M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:650-1:1300
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
    别名
    Cubilin (CUBN 产品)
    别名
    GP280 antibody, IFCR antibody, MGA1 antibody, AA408369 antibody, AL022750 antibody, D2Wsu88e antibody, gp280 antibody, cubilin antibody, cubilin (intrinsic factor-cobalamin receptor) antibody, LOC411053 antibody, CUBN antibody, cubn antibody, Cubn antibody
    背景
    Cubilin is an endocytic receptor that lacks a classical transmembrane region. It is a multidomain receptor that contains an amino terminal 110 residue segment followed by 8 epidermal growth factor (EGF)-like repeats and a contiguous stretch of 27 CUB domains. Cubilin acts as a receptor for intrinsic factor-vitamin B12 complexes. Cubilin is located within the epithelium of intestine and kidney. Mutations in Cubilin may play a role in autosomal recessive megaloblastic anemia also known as Imerslund-Grasbeck's disease, which causes intestinal malabsorption of vitamin B12.
    分子量
    399 kDa
    基因ID
    65969
    NCBI登录号
    NP_001074553
    UniProt
    Q9JLB4
    途径
    Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism
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