CHD1L antibody, ALC1 antibody, CHDL antibody, 4432404A22Rik antibody, Alc1 antibody, Snf2p antibody, zgc:56084 antibody, chromodomain helicase DNA binding protein 1 like antibody, chromodomain helicase DNA binding protein 1-like antibody, CHD1L antibody, chd1l antibody, Chd1l antibody
背景
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes, and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage.DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair.