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- 抗原 See all CD3 抗体
- CD3
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse CD3
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- 应用备注
- WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:250-1:1000/1:250-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." in: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).
: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).
: "Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection." in: International journal of biological sciences, Vol. 15, Issue 12, pp. 2719-2732, (2020) (PubMed).
: "
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The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." in: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).
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- 抗原
- CD3
- 别名
- CD3 (CD3 产品)
- 别名
- CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
- 背景
- The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.
- 分子量
- 21 kDa
- 基因ID
- 12501
- NCBI登录号
- NP_031674
- UniProt
- P22646
- 途径
- TCR Signaling, Ubiquitin Proteasome Pathway
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