CA13 is a cytosolic proteinmay that may play a role in embryogenesis and perturbation of its function by genetic modification could potentially lead to developmental abnormalities.Carbonic anhydrases (CAs) are zinc-containing metalloenzymes that catalyze reversible hydration of carbon dioxide. The mammalian α-CA gene family has been reported to include at least eleven enzymatically active isoforms with different structural and catalytic properties.