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BIRC3 抗体

BIRC3 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7073179
发货至: 中国
  • 抗原 See all BIRC3 抗体
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    适用
    • 67
    • 21
    • 5
    • 2
    小鼠, 大鼠
    宿主
    • 60
    • 6
    • 2
    克隆类型
    • 63
    • 5
    多克隆
    标记
    • 30
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIRC3 antibody is un-conjugated
    应用范围
    • 51
    • 33
    • 23
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse cIAP2
  • 应用备注
    WB (M,R) 1: 500-1: 1000, IHC/IF (M,R) 1:1500-1:3000/1:750-1:1500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
    别名
    cIAP2 (BIRC3 产品)
    别名
    AIP1 antibody, API2 antibody, CIAP2 antibody, HAIP1 antibody, HIAP1 antibody, MALT2 antibody, MIHC antibody, RNF49 antibody, c-IAP2 antibody, Api1 antibody, Api2 antibody, IAP1 antibody, IAP2 antibody, MIHB antibody, Birc2 antibody, HIAP2 antibody, MIAP1 antibody, MIAP2 antibody, cIAP1 antibody, cIAP2 antibody, cIAP-1 antibody, cIAP-2 antibody, AW107670 antibody, BIRC2 antibody, baculoviral IAP repeat containing 3 antibody, baculoviral IAP repeat-containing 3 antibody, baculoviral IAP repeat-containing protein 3 antibody, inhibitor of apoptosis protein-2 antibody, BIRC3 antibody, Birc3 antibody, LOC100399118 antibody, OpmnVgp074 antibody
    背景
    Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase dependent and caspase independent manner.
    分子量
    67 kDa
    基因ID
    11796
    NCBI登录号
    NP_031490
    UniProt
    O08863
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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