B-Cell Linker 抗体
Quick Overview for B-Cell Linker 抗体 (ABIN7073174)
抗原
See all B-Cell Linker (BLNK) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse BLNK
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anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-B-Cell Linker (BLNK) (AA 65-314) antibodyBLNK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 301-400) antibodyBLNK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-B-Cell Linker (BLNK) (C-Term) antibodyVerified BLNK 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK 适用: 人 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 41-337) antibodyBLNK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (N-Term) antibodyBLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr84) antibodyBLNK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) antibodyBLNK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC/IF (M,R) 1:2500-1:5000/1:1500-1:2500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- B-Cell Linker (BLNK)
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别名
- BLNK
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背景
- The function of BLNK was first illustrated in BLNK deficient DT40 cells, a chicken B-cell line, which exhibited an abrogated intracellular calcium mobilisation response and impaired activation of MAP kinases p38, JNK, and to a lesser degree ERK upon B-cell receptor (BCR) activation as compared to wild type DT40 cells. In knockout mice, BLNK deficiency results in a partial block in B-cell development, and in humans BLNK deficiency results in a much more profound block in B-cell development. Linker or adaptor proteins provide mechanisms by which receptors can amplify and regulate downstream effector proteins. The B-cell linker protein is essential for normal B-cell development.
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基因ID
- 17060
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NCBI登录号
- NP_032554
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UniProt
- Q9QUN3
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途径
- BCR Signaling
抗原
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