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- 抗原 See all WTX (AMER1) 抗体
- WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WTX antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse FAM123B
- Top Product
- Discover our top product AMER1 Primary Antibody
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anti-APC Membrane Recruitment Protein 1 (AMER1) antibody
AMER1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-APC Membrane Recruitment Protein 1 (AMER1) (AA 681-708) antibodyAMER1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18795 unconjugated
anti-APC Membrane Recruitment Protein 1 (AMER1) antibodyAMER1 适用: 人, 小鼠 IHC, WB, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB (H,M,R) 1: 500-1: 1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- WTX (AMER1) (APC Membrane Recruitment Protein 1 (AMER1))
- 别名
- FAM123B (AMER1 产品)
- 别名
- 2810002O09Rik antibody, AW492303 antibody, Fam123b antibody, Wtx antibody, FAM123B antibody, OSCS antibody, WTX antibody, RGD1560322 antibody, fam123b antibody, APC membrane recruitment 1 antibody, APC membrane recruitment protein 1 antibody, Amer1 antibody, AMER1 antibody, amer1 antibody
- 背景
- Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex. Acts both as a positive and negative regulator of the Wnt signaling pathway, depending on the context: acts as a positive regulator by promoting LRP6 phosphorylation. Also acts as a negative regulator by acting as a scaffold protein for the beta-catenin destruction complex and promoting stabilization of Axin at the cell membrane. Promotes CTNNB1 ubiquitination and degradation. Involved in kidney development.
- 分子量
- 125 kDa
- 基因ID
- 72345
- NCBI登录号
- NP_780388
- UniProt
- Q7TS75
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