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Recombinant CD53 抗体

CD53 适用: 人 FACS, IF, Func 宿主: 兔 Chimeric 161-2 unconjugated Recombinant Antibody
产品编号 ABIN7072633
发货至: 中国
  • 抗原 See all CD53 抗体
    CD53
    抗体类型
    Recombinant Antibody
    适用
    • 68
    • 5
    • 4
    宿主
    • 45
    • 25
    克隆类型
    • 46
    • 22
    • 2
    Chimeric
    标记
    • 31
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    • 5
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    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD53 antibody is un-conjugated
    应用范围
    • 48
    • 31
    • 28
    • 16
    • 13
    • 13
    • 10
    • 10
    • 9
    • 9
    • 5
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    原理
    Anti-CD53 [161-2 (53/2)], Rabbit IgG, kappa
    特异性
    This antibody recognizes human CD53. It does not react with the baboon and horse antigen. Cd53 is a member of tetraspanin family and is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins.
    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法
    Protein A affinity purified
    免疫原
    This antibody was raised by immunizng mice with stimulated human leukocytes.
    克隆位点
    161-2
    亚型
    IgG kappa
    Top Product
    Discover our top product CD53 Primary Antibody
  • 应用备注
    This antibody is recommended for the detection and analysis of CD53 via flow cytometry and immunofluorescence. Additionally, one group utilized this antibody for the ligation of the CD53 antigen while researching the potential involvement of tetraspanins (such as CD53) in tumor metastasis (Yunta et al., 2002). Furthermore, CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells, as it is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells.
    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    CD53
    别名
    CD53 (CD53 产品)
    背景
    Tetraspanin-25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tspan-25
    UniProt
    P19397
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