Recombinant CD226 抗体
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- 抗原 See all CD226 抗体
- CD226
- 抗体类型
- Recombinant Antibody
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- Chimeric
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标记
- This CD226 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-CD226 [10E5], Rabbit IgG, kappa
- 特异性
- This antibody is specific for murine CD226.
- 产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2b
- 纯化方法
- Protein A affinity purified
- 免疫原
- This antibody was raised by immunising Lewis and Lou/M rats with the murine Th1 cell clone AE7 and Th1 cell lines derived from 5B6 and DO11.10 TCR transgenic mice, before screening for reactivity with Th1 clones and a lack of reactivity to Th2/Th0 cell lines.
- 克隆位点
- 10E5
- 亚型
- IgG kappa
- Top Product
- Discover our top product CD226 Primary Antibody
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anti-CD226 (CD226) (AA 19-254) antibody
CD226 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (Tyr570) antibodyCD226 适用: 人, 小鼠, 猴 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 19-254) antibodyCD226 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8D11D5 unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal DX11 unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (AA 19-247) antibodyCD226 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM95 unconjugated
anti-CD226 (CD226) (AA 287-336), (pSer329) antibodyCD226 适用: 人, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (C-Term) antibodyCD226 适用: 人, 小鼠, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) antibodyCD226 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-CD226 (CD226) (pSer329) antibodyCD226 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The specificity of this antibody for murine CD226 has been confirmed in flow cytometric analysis using 293 cells transfected with CD226 cDNA and untransfected 293 cells (Dardalhon et al, 2005). This antibody has been used in flow cytometry to identify the surface expression pattern of CD226, which is predominantly confined to T cells (Dardalhon et al, 2005, Yasuma et al, 2016), and to detect NK cell CD226 expression and apoptosis (Huang et al, 2011). Immunisation of mice with this antibody inhibits antigen-specific T cell expansion (Dardalhon et al, 2005). Additionally, treatment of experimental autoimmune encephalomyelitis (EAE) mice with this antibody delays the onset and reduces the severity of Th1 cell-mediated autoimmune disease (Dardalhon et al, 2005).
- 说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- 抗原
- CD226
- 别名
- CD226 (CD226 产品)
- 背景
- DNAM-1, PTA1, PTA-1, platelet and T cell activation antigen 1, TLISA1
- UniProt
- Q8K4F0
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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