Recombinant CD96 抗体
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- 抗原 See all CD96 抗体
- CD96
- 抗体类型
- Recombinant Antibody
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- Chimeric
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标记
- This CD96 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Blocking Peptide (BP)
- 原理
- Anti-CD96 [6A6], Rabbit IgG, lambda
- 特异性
- This antibody is specific for murine CD96, and recognises an epitope in the first Ig domain.
- 产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
- 纯化方法
- Protein A affinity purified
- 免疫原
- This antibody was raised by immunising rats with murine CD96.
- 克隆位点
- 6A6
- 亚型
- IgG lambda
- Top Product
- Discover our top product CD96 Primary Antibody
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- 应用备注
- This antibody blocks murine CD96-CD155 interaction, and has been shown to bind to the first Ig domain of CD96 and compete with CD155 binding (Roman Aguilera et al, 2018). This antibody displays significant anti-metastatic activity in four experimental lung metastases models and one spontaneous tumour metastasis model (Roman Aguilera et al, 2018), with a potency greater than the anti-CD96 monoclonal antibodies 3.3 and 8B10. The binding specificity of this antibody has been determined in flow cytometric analysis of HEK-293 cells transfected with a range of CD96 Ig domain chimeric constructs (Roman Aguilera et al, 2018).
- 说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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