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Recombinant CD276 抗体 (Extracellular Domain)

CD276 适用: 小鼠 FACS, BR 宿主: 兔 Chimeric MJ18 unconjugated Recombinant Antibody
产品编号 ABIN7072434
发货至: 中国
  • 抗原 See all CD276 抗体
    CD276
    抗体类型
    Recombinant Antibody
    抗原表位
    • 15
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-242, Extracellular Domain
    适用
    • 63
    • 35
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 48
    • 16
    • 8
    • 1
    克隆类型
    • 43
    • 30
    Chimeric
    标记
    • 39
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD276 antibody is un-conjugated
    应用范围
    • 46
    • 24
    • 21
    • 14
    • 13
    • 10
    • 8
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Blocking Reagent (BR)
    原理
    Anti-B7-H3 [MJ18], Rabbit IgG, kappa
    特异性
    This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.
    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG1

    纯化方法
    Protein A affinity purified
    免疫原
    This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
    克隆位点
    MJ18
    亚型
    IgG kappa
    Top Product
    Discover our top product CD276 Primary Antibody
  • 应用备注
    This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    CD276
    别名
    B7-H3 (CD276 产品)
    背景
    CD276, B7H3
    UniProt
    Q8VE98
    途径
    Cancer Immune Checkpoints
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