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Recombinant Integrin beta 7 抗体

ITGB7 适用: 人, 小鼠 FACS, IF, BR 宿主: 兔 Chimeric FIB504 unconjugated Recombinant Antibody
产品编号 ABIN7072353
发货至: 中国
  • 抗原 See all Integrin beta 7 (ITGB7) 抗体
    Integrin beta 7 (ITGB7)
    抗体类型
    Recombinant Antibody
    适用
    • 61
    • 15
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 41
    • 12
    • 8
    • 4
    • 1
    克隆类型
    • 44
    • 21
    • 1
    Chimeric
    标记
    • 35
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Integrin beta 7 antibody is un-conjugated
    应用范围
    • 38
    • 23
    • 22
    • 13
    • 13
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Blocking Reagent (BR)
    原理
    Anti-Integrin beta-7 [FIB504], Rabbit IgG, kappa
    特异性
    FIB504 recognizes an epitope on intergin beta-7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
    交叉反应
    小鼠
    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    纯化方法
    Protein A affinity purified
    免疫原
    FIB504 was prepared by immunizing rats with TK1 cells.
    克隆位点
    FIB504
    亚型
    IgG kappa
    Top Product
    Discover our top product ITGB7 Primary Antibody
  • 应用备注
    FIB504 can be used for IF, FC and can block TKI cell aggregation and beta-7 intergrin-mediated cell adhesion.
    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    Integrin beta 7 (ITGB7)
    别名
    Integrin beta-7 (ITGB7 产品)
    背景
    FIB-27, FIB 27, Fib-27, Fib27, Fib 27, fib27, fib-27, fib 27, Integrin b7, integrin b-7, ITGB7, Gut homing receptor beta subunit
    UniProt
    P26011
    途径
    Integrin Complex
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