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Recombinant G Protein-Coupled Receptor 119 抗体

GPR119 适用: 人, 小鼠, 大鼠, 犬 ELISA, IF, BP 宿主: 小鼠 Monoclonal Gipg013 unconjugated Recombinant Antibody
产品编号 ABIN7072310
发货至: 中国
  • 抗原 See all G Protein-Coupled Receptor 119 (GPR119) 抗体
    G Protein-Coupled Receptor 119 (GPR119)
    抗体类型
    Recombinant Antibody
    适用
    • 17
    • 5
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 18
    • 1
    • 1
    小鼠
    克隆类型
    • 17
    • 2
    • 1
    单克隆
    标记
    • 20
    This G Protein-Coupled Receptor 119 antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 12
    • 10
    • 5
    • 3
    • 2
    • 2
    ELISA, Immunofluorescence (IF), Blocking Peptide (BP)
    原理
    Anti-Glucose-dependent insulinotropic Receptor [Gipg013], Mouse IgG2a, lambda
    特异性
    The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.
    交叉反应
    犬, 小鼠, 大鼠
    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: scFv

    纯化方法
    Protein A affinity purified
    免疫原
    Human GIPr.
    克隆位点
    Gipg013
    亚型
    IgG2a lambda
    Top Product
    Discover our top product GPR119 Primary Antibody
  • 应用备注
    This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81 % .
    说明

    This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    G Protein-Coupled Receptor 119 (GPR119)
    别名
    Glucose-dependent insulinotropic Receptor (GPR119 产品)
    背景
    GIPr
    UniProt
    Q8TDV5
    途径
    Hormone Transport, Peptide Hormone Metabolism
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