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p53 抗体 (pThr81) (Cy7)

TP53 适用: 人 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN703021
发货至: 中国
  • 抗原 See all p53 (TP53) 抗体
    p53 (TP53) (Tumor Protein P53 (TP53))
    抗原表位
    • 43
    • 40
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    pThr81
    适用
    • 823
    • 252
    • 208
    • 104
    • 47
    • 33
    • 31
    • 18
    • 10
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    • 1
    • 1
    • 1
    宿主
    • 622
    • 218
    • 6
    • 2
    • 1
    克隆类型
    • 558
    • 290
    • 1
    多克隆
    标记
    • 477
    • 38
    • 31
    • 19
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    • 13
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    • 1
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    This p53 antibody is conjugated to Cy7
    应用范围
    • 661
    • 298
    • 246
    • 200
    • 199
    • 148
    • 123
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    • 118
    • 64
    • 59
    • 32
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Mouse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Thr81
    亚型
    IgG
    Top Product
    Discover our top product TP53 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    p53 (TP53) (Tumor Protein P53 (TP53))
    别名
    P53 (TP53 产品)
    背景

    Synonyms: p53 Thr81, P53 phospho T81, P53 phospho Thr81, p-P53 Thr81, p-P53 T81, Widespread p53, Wtp53, Antigen NY-CO-13, Cellular tumor antigen p53, Cys 51 Stop, HGNC11998, LFS1, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, Phosphoprotein p53, TP53, Transformation related protein 53, TRP53, Tumor protein p53, Tumour Protein p53, P53_HUMAN, TP53.

    Background: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].

    基因ID
    7157
    途径
    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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