KEAP1 抗体 (AA 65-160)
(5 references)-
- 抗原 See all KEAP1 抗体
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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抗原表位
- AA 65-160
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适用
- 人, 小鼠, 大鼠, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KEAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, Pig, 兔, 大鼠
- 预测反应
- Dog,Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KEAP1
- 亚型
- IgG
- Top Product
- Discover our top product KEAP1 Primary Antibody
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anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KEAP1 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7G4B10 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibodyKEAP1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F10B6 unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibodyKEAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (C-Term) antibodyKEAP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibodyKEAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibodyVerified KEAP1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-624) antibodyKEAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 327-624) antibodyKEAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (N-Term) antibodyKEAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "The electrophilic character of quinones is essential for the suppression of Bach1." in: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).
: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).
: "Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154210, (2016) (PubMed).
: "Tetrachlorobenzoquinone activates nrf2 signaling by keap1 cross-linking and ubiquitin translocation but not keap1-cullin3 complex dissociation." in: Chemical research in toxicology, Vol. 28, Issue 4, pp. 765-74, (2015) (PubMed).
: "Neohesperidin Dihydrochalcone versus CCl?-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation." in: Journal of agricultural and food chemistry, Vol. 63, Issue 22, pp. 5468-75, (2015) (PubMed).
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: "The electrophilic character of quinones is essential for the suppression of Bach1." in: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).
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- 抗原
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- 别名
- KEAP1 (KEAP1 产品)
- 别名
- INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
- 背景
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Synonyms: INrf2, KLHL19, Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1, KIAA0132
Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
- 基因ID
- 9817
- UniProt
- Q14145
- 途径
- Maintenance of Protein Location
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