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TLN1 抗体 (AA 1601-1750)

TLN1 适用: 小鼠, 大鼠 ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN701695
发货至: 中国
  • 抗原 See all TLN1 抗体
    TLN1 (Talin 1 (TLN1))
    抗原表位
    • 14
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1601-1750
    适用
    • 45
    • 39
    • 27
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 45
    • 15
    • 1
    • 1
    克隆类型
    • 47
    • 15
    多克隆
    标记
    • 34
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLN1 antibody is un-conjugated
    应用范围
    • 33
    • 23
    • 12
    • 12
    • 9
    • 8
    • 8
    • 6
    • 5
    • 3
    • 2
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Talin 1.
    亚型
    IgG
    Top Product
    Discover our top product TLN1 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • He, Meng, Yao, Jiang, Wu, Wu: "The essential role of inorganic substrate in the migration and osteoblastic differentiation of mesenchymal stem cells." in: Journal of the mechanical behavior of biomedical materials, Vol. 59, pp. 353-65, (2016) (PubMed).

    Dingyu, Fanjie, Zhengzheng, Baosheng, Chao, Yi, Huiwen, Jun, Gang: "Regulation of Intracellular Structural Tension by Talin in the Axon Growth and Regeneration." in: Molecular neurobiology, (2015) (PubMed).

  • 抗原
    TLN1 (Talin 1 (TLN1))
    别名
    Talin1 (TLN1 产品)
    别名
    ILWEQ antibody, TLN antibody, Tln antibody, sb:cb854 antibody, wu:fb05c02 antibody, TLN1 antibody, talin-1 antibody, tln antibody, talin 1 antibody, talin 1 L homeolog antibody, Talin 1 antibody, talin-1 antibody, TLN1 antibody, Tln1 antibody, tln1 antibody, tln1.L antibody, Bm1_56490 antibody, LOC100380665 antibody
    背景

    Synonyms: TLN 1, ILWEQ, Talin 1, Talin, TLN, TLN1, TLN 2, Talin 2, Talin 2, TLN2.

    Background: Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-270 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin. Talin and vinculin have been shown to interact with each other and both have been proposed to be involved in generating the transmembrane connection, between the extracellular matrix and the cytoskeleton, that occurs at adhesion plaques. At physiological ionic strength, talin is an elongate, flexible, monomeric protein with the ability to self-associate into dimers at higher protein concentrations.

    基因ID
    7094, 83660
    UniProt
    Q9Y4G6, Q9Y490
    途径
    Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location
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