CD32/CD16 抗体 (FITC)
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- 抗原 See all CD32/CD16 products
- CD32/CD16
- 适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD32/CD16 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
- 纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Murine pre-B cells
- 克隆位点
- 93
- 亚型
- IgG2a lambda
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- 应用备注
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- CD32/CD16
- 别名
- CD16/CD32 (CD32/CD16 产品)
- 背景
- CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Unlike human, the murine protein is expressed only as a transmembrane isoform. Also CD32 (FcgammaRII) is a low affinity receptor for IgG, but its affinity is lower than that of CD16. These receptors are expressed on monocytes/macrophages, NK cells, granulocytes, mast cells, dendritic cells, and B cells. Their role is to mediate adaptive immune responses through binding the antibody-antigen immunocomplexes, but their effect on the particular cell differs according to the cell type.,CD16, CD32, FcgammaRIII, FCgammaRII, FCGR3, FCGR2
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