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CD24 抗体 (PE-DyLight 594)

CD24 适用: 人 FACS 宿主: 小鼠 Monoclonal SN3 PE-DyLight 594
产品编号 ABIN7013984
发货至: 中国
  • 抗原 See all CD24 抗体
    CD24 (CD24 Molecule (CD24))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD24 antibody is conjugated to PE-DyLight 594
    应用范围
    • 90
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    Flow Cytometry (FACS)
    特异性
    The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.
    纯化方法
    Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-DyLight®594 (PE-DyLight®594) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Glycoproteins purified from human NALM-1 cell line.
    克隆位点
    SN3
    亚型
    IgG1
    Top Product
    Discover our top product CD24 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    CD24 (CD24 Molecule (CD24))
    别名
    CD24 (CD24 产品)
    别名
    CD24A antibody, Cd24a antibody, CD24 molecule antibody, CD24 antibody, Cd24 antibody
    背景
    CD24 Molecule,CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.,HSA, nectadorin, SCLC4
    基因ID
    100133941
    UniProt
    P25063
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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