CD24 抗体 (PE-DyLight 594)
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- 抗原 See all CD24 抗体
- CD24 (CD24 Molecule (CD24))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD24 antibody is conjugated to PE-DyLight 594
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.
- 纯化方法
- Purified antibody is conjugated with activated tandem dye of R-phycoerythrin-DyLight®594 (PE-DyLight®594) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Glycoproteins purified from human NALM-1 cell line.
- 克隆位点
- SN3
- 亚型
- IgG1
- Top Product
- Discover our top product CD24 Primary Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- CD24 (CD24 Molecule (CD24))
- 别名
- CD24 (CD24 产品)
- 别名
- CD24A antibody, Cd24a antibody, CD24 molecule antibody, CD24 antibody, Cd24 antibody
- 背景
- CD24 Molecule,CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.,HSA, nectadorin, SCLC4
- 基因ID
- 100133941
- UniProt
- P25063
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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