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ITGA5 抗体

ITGA5 适用: 小鼠 FACS, IHC (fro), ICC, Func 宿主: 大鼠 Monoclonal 5H10-27 (MFR5) unconjugated
产品编号 ABIN7013949
发货至: 中国
  • 抗原 See all ITGA5 抗体
    ITGA5 (Integrin, alpha 5 (ITGA5))
    适用
    • 111
    • 69
    • 22
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    小鼠
    宿主
    • 93
    • 19
    • 9
    • 4
    大鼠
    克隆类型
    • 86
    • 40
    单克隆
    标记
    • 58
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    This ITGA5 antibody is un-conjugated
    应用范围
    • 81
    • 51
    • 42
    • 33
    • 14
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)
    特异性
    The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e, a 135 kDa protein serving as VLA-5 alpha chain, expressed on thymocytes, activated T cells, splenic B cells, and mast cells.
    纯化方法
    Purified by protein-G affinity chromatography.
    免疫原
    C57BL/6 x A/J)F1 murine mast cell line
    克隆位点
    5H10-27 (MFR5)
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ITGA5 Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Functional application: Blocking
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    ITGA5 (Integrin, alpha 5 (ITGA5))
    别名
    CD49e (ITGA5 产品)
    别名
    ITGA5 antibody, Cd49e antibody, Fnra antibody, VLA5 antibody, CD49e antibody, FNRA antibody, VLA5A antibody, Itga5_retired antibody, integrin subunit alpha 5 antibody, integrin alpha 5 (fibronectin receptor alpha) antibody, ITGA5 antibody, Itga5 antibody
    背景
    Integrin alpha 5,CD49e, the alpha 5 integrin, noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin, and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers, in monocyte migration into the extracellular tissues, and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis.,ITGA5, VLA-5 alpha, FNRA
    基因ID
    16402
    UniProt
    P11688
    途径
    Integrin Complex
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