CD77 抗体
This anti-CD77 antibody is a 大鼠 单克隆 antibody detecting CD77 in FACS, ICC 和 IHC (fro). Suitable for 人.
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Quick Overview for CD77 抗体 (ABIN7013943)
抗原
CD77
适用
人
宿主
大鼠
克隆类型
单克隆
标记
This CD77 antibody is un-conjugated
应用范围
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
克隆位点
38-13
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原理
- Anti-Hu CD77 Purified
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特异性
- The rat monoclonal antibody 38.13 recognizes CD77 (globotriaosylceramide Gb3), a neutral glycosphingolipid expressed mainly on the surface of B cell populations, such as germinal center B cells and Burkitt´s lymphoma cells.
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纯化方法
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
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免疫原
- Daudi cell line (Burkitt´s lymphoma)
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亚型
- IgM
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anti-CD77 antibody (FITC)
适用: 人 FACS 宿主: 大鼠 Monoclonal 38-13 FITC
anti-CD77 antibody (PE)适用: 人 FACS 宿主: 大鼠 Monoclonal 38-13 PE
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应用备注
- Flow cytometry: Recommended dilution: 1 μg/mL
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD77
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背景
- CD77 (globotriaosylceramide Gb3), also known as the Pk blood group antigen, BLA (Burkitt´s lymphoma associated antigen), or CTH (ceramide trihexoside) is a neutral glycosphingolipid composed of three carbohydrate molecules linked to a lipid moiety in the cell membrane (Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer). It is expressed on germinal center B cells, Burkitt´s lymphoma cells, it can be induced on extrafolicular B cells and it is also found on endothelia and epithelia. CD77 may be involved in elimination of germinal center B cells that fail to produce high affinity antibodies, and serves also as receptor for shiga toxin and verotoxin.,globotriaosylceramide Gb3, Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer, P blood group
抗原
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