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GZMB 抗体 (FITC)

GZMB 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal CLB-GB11 FITC
产品编号 ABIN7013929
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    适用
    • 125
    • 48
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    人, Non-Human Primate
    宿主
    • 83
    • 44
    • 2
    小鼠
    克隆类型
    • 81
    • 48
    单克隆
    标记
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    This GZMB antibody is conjugated to FITC
    应用范围
    • 71
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
    纯化方法
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Human NK cell line YT-INDY-derived granzyme B
    克隆位点
    CLB-GB11
    亚型
    IgG1
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    GZMB (Granzyme B (GZMB))
    别名
    Granzyme B (GZMB 产品)
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景
    Granzyme B,Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.,GZMB, HLP, CTLA1, SECT
    基因ID
    3002
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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