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HLA-E 抗体 (PE)

HLA-E 适用: 人 FACS 宿主: 小鼠 Monoclonal 3D12 PE
产品编号 ABIN7013921
发货至: 中国
  • 抗原 See all HLA-E 抗体
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    适用
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    宿主
    • 47
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    小鼠
    克隆类型
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    单克隆
    标记
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    This HLA-E antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody 3D12 (also known as 3D12HLA-E) recognizes native extracellular part of HLA-E, an ubiquitously expressed non-classical MHC class I molecule, as well as free HLA-E.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    recombinant human HLA-E
    克隆位点
    3D12
    亚型
    IgG1
    Top Product
    Discover our top product HLA-E Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    别名
    HLA-E (HLA-E 产品)
    别名
    EA1.2 antibody, EA2.1 antibody, HLA-6.2 antibody, MHC antibody, QA1 antibody, major histocompatibility complex, class I, E antibody, HLA-E antibody, PATR-E antibody
    背景
    Major histocompatibility complex, class I, E,HLA-E (human leukocyte antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells).,HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E
    基因ID
    3133
    UniProt
    P13747
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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