TCR alpha/beta 抗体
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- 抗原 See all TCR alpha/beta products
- TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
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适用
- 大鼠, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TCR alpha/beta antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Immunocytochemistry (ICC)
- 特异性
- The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
- 纯化方法
- Purified by protein-A affinity chromatography.
- 内毒素水平
- Low Endotoxin
- 免疫原
- Rat T blasts and erythrocytes
- 克隆位点
- R73
- 亚型
- IgG1 kappa
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- 应用备注
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Flow cytometry: Recommended dilution: 1-4 μg/mL.
Functional application: In vitro activation and in vivo depletion of alpha/beta TCR T cells. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
- 别名
- TCR alpha/beta (TCR alpha/beta 产品)
- 背景
- The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
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