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Phospholamban 抗体 (pThr17)

PLN 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7265288
发货至: 中国
  • 抗原 See all Phospholamban (PLN) 抗体
    Phospholamban (PLN)
    抗原表位
    • 30
    • 18
    • 17
    • 9
    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pThr17
    适用
    • 83
    • 25
    • 24
    • 3
    • 2
    • 2
    • 2
    人, 大鼠, 小鼠
    宿主
    • 83
    • 1
    • 1
    克隆类型
    • 85
    多克隆
    标记
    • 32
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Phospholamban antibody is un-conjugated
    应用范围
    • 34
    • 26
    • 26
    • 24
    • 12
    • 9
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Phosphorylated antibody
    纯化方法
    Affinity purification
    免疫原
    A phospho specific peptide corresponding to residues surrounding T17 of human PLN
    亚型
    IgG
    Top Product
    Discover our top product PLN Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Phospholamban (PLN)
    别名
    PLN (PLN 产品)
    别名
    LOC100226261 antibody, plb antibody, cmd1p antibody, CMD1P antibody, CMH18 antibody, PLB antibody, Plb antibody, Plm antibody, phospholamban antibody, PLN antibody, pln antibody, Pln antibody
    背景
    The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
    基因ID
    5350
    UniProt
    P26678
    途径
    Negative Regulation of Transporter Activity
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