POLR2A/RPB1 抗体 (pSer5)
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- 抗原 See all POLR2A/RPB1 (POLR2A) 抗体
- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
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抗原表位
- pSer5
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR2A/RPB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Phosphorylated antibody
- 纯化方法
- Affinity purification
- 免疫原
- A phospho specific peptide corresponding to residues surrounding S5 of human POLR2A
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
- 别名
- POLR2A (POLR2A 产品)
- 背景
- This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
- 分子量
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Observed_MW: 260 kDa
Calculated_MW: 63 kDa/217 kDa
- 基因ID
- 5430
- UniProt
- P24928
- 途径
- Regulatory RNA Pathways
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