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p53 抗体 (pSer33)

TP53 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7265276
发货至: 中国
  • 抗原 See all p53 (TP53) 抗体
    p53 (TP53) (Tumor Protein P53 (TP53))
    抗原表位
    • 51
    • 45
    • 42
    • 35
    • 35
    • 29
    • 27
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    • 3
    pSer33
    适用
    • 892
    • 263
    • 221
    • 114
    • 47
    • 34
    • 31
    • 18
    • 10
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    • 3
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    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 686
    • 222
    • 6
    • 2
    • 1
    克隆类型
    • 640
    • 276
    • 1
    多克隆
    标记
    • 486
    • 47
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p53 antibody is un-conjugated
    应用范围
    • 698
    • 335
    • 246
    • 217
    • 194
    • 147
    • 124
    • 119
    • 119
    • 64
    • 54
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Phosphorylated antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic phosphorylated peptide around S33 of human p53 (NP_000537.3).
    亚型
    IgG
    Top Product
    Discover our top product TP53 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    p53 (TP53) (Tumor Protein P53 (TP53))
    别名
    p53 (TP53 产品)
    别名
    BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
    背景
    This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).
    分子量

    Observed_MW: 55 kDa

    Calculated_MW: 23-43 kDa

    基因ID
    7157
    UniProt
    P04637
    途径
    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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