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IGF1R 抗体 (pTyr1161)

IGF1R 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7265182
发货至: 中国
  • 抗原 See all IGF1R 抗体
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    抗原表位
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    pTyr1161
    适用
    • 183
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    人, 小鼠, 大鼠
    宿主
    • 168
    • 29
    • 2
    • 1
    克隆类型
    • 170
    • 30
    多克隆
    标记
    • 127
    • 8
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    This IGF1R antibody is un-conjugated
    应用范围
    • 133
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Phosphorylated antibody
    纯化方法
    Affinity purification
    免疫原
    A phospho specific peptide corresponding to residues surrounding Y1161 of human IGF1R
    亚型
    IgG
    Top Product
    Discover our top product IGF1R Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    别名
    IGF1R (IGF1R 产品)
    背景
    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    分子量

    Observed_MW: 95 kDa

    Calculated_MW: 154 kDa

    基因ID
    3480
    UniProt
    P08069
    途径
    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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