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CHEK1 抗体 (pSer280)
CHEK1
适用: 人, 小鼠, 大鼠
IHC, IF
宿主: 兔
Polyclonal
unconjugated
CHEK1抗体详情
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抗原
See all CHEK1 抗体
CHEK1
(Checkpoint Kinase 1 (CHEK1))
抗原表位
All epitopes for CHEK1 抗体
pSer280
适用
All reactivities for CHEK1 抗体
人, 小鼠, 大鼠
宿主
All hosts for CHEK1 抗体
兔
克隆类型
All clonalities for CHEK1 抗体
多克隆
标记
All conjugates for CHEK1 抗体
This CHEK1 antibody is un-conjugated
应用范围
All applications for CHEK1 抗体
Immunohistochemistry (IHC), Immunofluorescence (IF)
产品特性
Phosphorylated antibody
纯化方法
Affinity purification
免疫原
A synthetic phosphorylated peptide around S280 of human CHEK1 (NP_001265.2).
亚型
IgG
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Discover our top product CHEK1 Primary Antibody
Alternatives
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使用细节
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应用备注
IHC 1:50-1:200 IF 1:50-1:200
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
CHEK1目标详情
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抗原
CHEK1
(Checkpoint Kinase 1 (CHEK1))
别名
CHEK1 (CHEK1 产品 )
别名
An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
背景
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
基因ID
1111
UniProt
O14757
途径
p53 Pathway , Apoptosis , Cell Division Cycle , DNA Damage Repair
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