DROSHA 抗体
-
- 抗原 See all DROSHA 抗体
- DROSHA (Drosha, Ribonuclease Type III (DROSHA))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DROSHA antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human DROSHA (NP_037367.3).
- 亚型
- IgG
- Top Product
- Discover our top product DROSHA Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000 IF 1:50-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- DROSHA (Drosha, Ribonuclease Type III (DROSHA))
- 别名
- DROSHA (DROSHA 产品)
- 别名
- im:7150667 antibody, zgc:158612 antibody, ETOHI2 antibody, HSA242976 antibody, RANSE3L antibody, RN3 antibody, RNASE3L antibody, RNASEN antibody, 1110013A17Rik antibody, AI874853 antibody, Etohi2 antibody, Rn3 antibody, Rnasen antibody, RGD1307626 antibody, ribonuclease type III, nuclear antibody, Ribonuclease 3 antibody, ribonuclease 3 antibody, drosha ribonuclease III antibody, drosha, ribonuclease type III antibody, rnasen antibody, Thicy_0885 antibody, Sinme_0866 antibody, Isova_2087 antibody, Sphch_0770 antibody, DROSHA antibody, Drosha antibody
- 背景
- This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
- 分子量
-
Observed_MW: 180 kDa
Calculated_MW: 138 kDa/151 kDa/155 kDa/159 kDa
- 基因ID
- 29102
- UniProt
- Q9NRR4
- 途径
- Regulatory RNA Pathways
-