EXOC2 抗体
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- 抗原 See all EXOC2 抗体
- EXOC2 (Exocyst Complex Component 2 (EXOC2))
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适用
- 小鼠, 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EXOC2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human EXOC2 (NP_060773.3).
- 亚型
- IgG
- Top Product
- Discover our top product EXOC2 Primary Antibody
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- 应用备注
- WB 1:500-1:2000 IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- EXOC2 (Exocyst Complex Component 2 (EXOC2))
- 别名
- EXOC2 (EXOC2 产品)
- 别名
- CG8843 antibody, Dmel\\CG8843 antibody, Sec-5 antibody, Sec5 antibody, Sec5p antibody, dsec5 antibody, SEC5 antibody, SEC5L1 antibody, 2410030I24Rik antibody, AI648199 antibody, Sec5l1 antibody, Rsec5 antibody, F7O12.2 antibody, F7O12_2 antibody, exocyst complex component sec5 antibody, Secretory 5 antibody, exocyst complex component 2 antibody, exocyst complex component sec5 antibody, Exocyst complex component 2 antibody, Sec5 antibody, EXOC2 antibody, Exoc2 antibody, SEC5A antibody, sec-5 antibody
- 背景
- The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 108 kDa
Calculated_MW: 104 kDa
- 基因ID
- 55770
- UniProt
- Q96KP1
- 途径
- Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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