MBNL1 抗体
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- 抗原 See all MBNL1 抗体
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBNL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein of human MBNL1 (NP_066368.2).
- 亚型
- IgG
- Top Product
- Discover our top product MBNL1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- 别名
- MBNL1 (MBNL1 产品)
- 别名
- MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody
- 背景
- This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
- 分子量
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Observed_MW: 42 kDa
Calculated_MW: 33 kDa/34 kDa/36 kDa/37 kDa/39 kDa/40 kDa/41 kDa
- 基因ID
- 4154
- UniProt
- Q9NR56
- 途径
- Ribonucleoprotein Complex Subunit Organization
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