MORF4L2 抗体
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- 抗原 See all MORF4L2 抗体
- MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MORF4L2 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human MORF4L2 (NP_001135890.1).
- 亚型
- IgG
- Top Product
- Discover our top product MORF4L2 Primary Antibody
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- 应用备注
- IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))
- 别名
- MORF4L2 (MORF4L2 产品)
- 别名
- morf4l2 antibody, MORF4L2 antibody, DKFZp468A0820 antibody, MORFL2 antibody, MRGX antibody, 2410017O14Rik antibody, Mrgx antibody, Sid393p antibody, mKIAA0026 antibody, LRRG00119 antibody, mortality factor 4 like 1 antibody, mortality factor 4 like 2 antibody, morf4l1 antibody, MORF4L2 antibody, Morf4l2 antibody
- 背景
- Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
- 基因ID
- 9643
- UniProt
- Q15014
- 途径
- Regulation of Muscle Cell Differentiation
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