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LIM Domain Binding 3 Protein 抗体

LDB3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7263475
发货至: 中国
  • 抗原 See all LIM Domain Binding 3 Protein (LDB3) 抗体
    LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
    适用
    • 21
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 18
    • 4
    • 1
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIM Domain Binding 3 Protein antibody is un-conjugated
    应用范围
    • 23
    • 14
    • 4
    • 4
    • 1
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human LDB3 (NP_001073585.1).
    亚型
    IgG
    Top Product
    Discover our top product LDB3 Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))
    别名
    LDB3 (LDB3 产品)
    背景
    This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
    基因ID
    11155
    UniProt
    O75112
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