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OAZ1 抗体

OAZ1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7263455
发货至: 中国
  • 抗原 See all OAZ1 抗体
    OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
    适用
    人, 小鼠, 大鼠
    宿主
    • 17
    • 1
    克隆类型
    • 18
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OAZ1 antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 6
    • 2
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human OAZ1 (NP_004143.1).
    亚型
    IgG
    Top Product
    Discover our top product OAZ1 Primary Antibody
  • 应用备注
    IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    OAZ1 (Ornithine Decarboxylase Antizyme 1 (OAZ1))
    别名
    OAZ1 (OAZ1 产品)
    别名
    AZI antibody, OAZ antibody, AZ-1 antibody, AZ1 antibody, Antizyme antibody, ODC-Az antibody, Oaz antibody, ODCAC antibody, oaz antibody, AZS antibody, oaz1 antibody, ornithine decarboxylase antizyme 1 antibody, ornithine decarboxylase antizyme 1 S homeolog antibody, ornithine decarboxylase antizyme 1a antibody, OAZ1 antibody, Oaz1 antibody, oaz1.S antibody, oaz1a antibody
    背景
    The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis, thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs, and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene.
    基因ID
    4946
    UniProt
    P54368
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