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CARD11 抗体

CARD11 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7263125
发货至: 中国
  • 抗原 See all CARD11 抗体
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    适用
    • 33
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 31
    • 1
    • 1
    • 1
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 27
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD11 antibody is un-conjugated
    应用范围
    • 27
    • 10
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human CARD11 (NP_115791.3).
    亚型
    IgG
    Top Product
    Discover our top product CARD11 Primary Antibody
  • 应用备注
    IHC 1:50-1:200 IF 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
    别名
    CARD11 (CARD11 产品)
    背景
    The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
    基因ID
    84433
    UniProt
    Q9BXL7
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling
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