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TRIM33 抗体 (AA 981-1127)

TRIM33 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN701140
发货至: 中国
  • 抗原 See all TRIM33 抗体
    TRIM33 (Tripartite Motif Containing 33 (TRIM33))
    抗原表位
    • 16
    • 15
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 981-1127
    适用
    • 71
    • 34
    • 23
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 59
    • 12
    克隆类型
    • 60
    • 11
    多克隆
    标记
    • 31
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRIM33 antibody is un-conjugated
    应用范围
    • 42
    • 33
    • 13
    • 12
    • 12
    • 12
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TIF1 gamma
    亚型
    IgG
    Top Product
    Discover our top product TRIM33 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    TRIM33 (Tripartite Motif Containing 33 (TRIM33))
    别名
    T1 gamma (TRIM33 产品)
    别名
    TRIM33 antibody, ptc7 antibody, rfg7 antibody, tf1g antibody, tif1g antibody, tifgamma antibody, MGC146665 antibody, tif1gamma antibody, ECTO antibody, PTC7 antibody, RFG7 antibody, TF1G antibody, TIF1G antibody, TIF1GAMMA antibody, TIFGAMMA antibody, ecto antibody, 8030451N04Rik antibody, AI413936 antibody, Ecto antibody, Tif1g antibody, ectodermin antibody, mKIAA1113 antibody, cb1085 antibody, id:ibd2175 antibody, mon antibody, wu:fc17f10 antibody, zgc:136680 antibody, tripartite motif containing 33 antibody, tripartite motif containing 33 L homeolog antibody, tripartite motif-containing 33 antibody, TRIM33 antibody, trim33 antibody, trim33.L antibody, Trim33 antibody
    背景

    Synonyms: ECTO, PTC7, RFG7, TF1G, TIF1G, TIFGAMMA, TIF1GAMMA, E3 ubiquitin-protein ligase TRIM33, Ectodermin homolog, RET-fused gene 7 protein, Protein Rfg7, Transcription intermediary factor 1-gamma, TIF1-gamma, Tripartite motif-containing protein 33, TRIM33, KIAA1113

    Background: Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).

    基因ID
    51592
    UniProt
    Q9UPN9
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