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MUS81 抗体

MUS81 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7262745
发货至: 中国
  • 抗原 See all MUS81 抗体
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    适用
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 14
    • 1
    克隆类型
    • 15
    多克隆
    标记
    • 11
    • 2
    • 1
    • 1
    This MUS81 antibody is un-conjugated
    应用范围
    • 9
    • 6
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human MUS81 (NP_079404.3).
    亚型
    IgG
    Top Product
    Discover our top product MUS81 Primary Antibody
  • 应用备注
    IHC 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    别名
    MUS81 (MUS81 产品)
    背景
    This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
    基因ID
    80198
    UniProt
    Q96NY9
    途径
    DNA Damage Repair
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