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PYGL 抗体

PYGL 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7262605
发货至: 中国
  • 抗原 See all PYGL 抗体
    PYGL (phosphorylase, Glycogen, Liver (PYGL))
    适用
    • 53
    • 19
    • 12
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 60
    • 2
    克隆类型
    • 60
    • 2
    多克隆
    标记
    • 19
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PYGL antibody is un-conjugated
    应用范围
    • 29
    • 20
    • 13
    • 13
    • 13
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human PYGL (NP_002854.3).
    亚型
    IgG
    Top Product
    Discover our top product PYGL Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PYGL (phosphorylase, Glycogen, Liver (PYGL))
    别名
    PYGL (PYGL 产品)
    别名
    zgc:66314 antibody, GSD6 antibody, glycogen phosphorylase L antibody, phosphorylase, glycogen, liver antibody, phosphorylase, glycogen, liver S homeolog antibody, liver glycogen phosphorylase antibody, PYGL antibody, pygl antibody, pygl.S antibody, Pygl antibody
    背景
    This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively. The liver isozyme serves the glycemic demands of the body in general while the brain and muscle isozymes supply just those tissues. In glycogen storage disease type VI, also known as Hers disease, mutations in liver glycogen phosphorylase inhibit the conversion of glycogen to glucose and results in moderate hypoglycemia, mild ketosis, growth retardation and hepatomegaly. Alternative splicing results in multiple transcript variants encoding different isoforms.
    基因ID
    5836
    UniProt
    P06737
    途径
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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