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COCH 抗体

COCH 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7262425
发货至: 中国
  • 抗原 See all COCH 抗体
    COCH (Cochlin (COCH))
    适用
    • 48
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 46
    • 2
    克隆类型
    • 48
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COCH antibody is un-conjugated
    应用范围
    • 38
    • 27
    • 15
    • 13
    • 2
    • 2
    • 2
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human COCH (NP_001128530.1).
    亚型
    IgG
    Top Product
    Discover our top product COCH Primary Antibody
  • 应用备注
    IHC 1:50-1:100 IF 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    COCH (Cochlin (COCH))
    别名
    COCH (COCH 产品)
    别名
    AW122937 antibody, Coch-5B2 antibody, D12H14S564E antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody, cochlin antibody, Coch antibody, COCH antibody
    背景
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated.
    基因ID
    1690
    UniProt
    O43405
    途径
    Sensory Perception of Sound
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