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BAP1 抗体

BAP1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7262383
发货至: 中国
  • 抗原 See all BAP1 抗体
    BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
    适用
    • 66
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    人, 大鼠, 小鼠
    宿主
    • 66
    • 16
    克隆类型
    • 67
    • 15
    多克隆
    标记
    • 40
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    This BAP1 antibody is un-conjugated
    应用范围
    • 39
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human BAP1 (NP_004647.1).
    亚型
    IgG
    Top Product
    Discover our top product BAP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))
    别名
    BAP1 (BAP1 产品)
    别名
    HUCEP-13 antibody, UCHL2 antibody, BAIAP3 antibody, 2300006C11Rik antibody, AA989761 antibody, AW553466 antibody, mKIAA0272 antibody, uch-x4 antibody, hucep-13 antibody, hucep-6 antibody, uchl2 antibody, si:dkey-42i9.9 antibody, BRCA1 associated protein 1 antibody, Brca1 associated protein 1 antibody, BRCA1 associated protein 1 L homeolog antibody, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody, BAP1 antibody, Bap1 antibody, bap1.L antibody, bap1 antibody
    背景
    This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
    分子量

    Observed_MW: 80 kDa

    Calculated_MW: 80 kDa

    基因ID
    8314
    UniProt
    Q92560
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