COX antibody, COX-VA antibody, VA antibody, CG14724 antibody, COXA_DROME antibody, Dmel\\CG14724 antibody, Va antibody, tend antibody, cox5a antibody, cb01f09 antibody, mg:cb01f09 antibody, GB15816 antibody, MGC79007 antibody, Afu5g02750 antibody, wu:fj32b09 antibody, zgc:109989 antibody, zgc:114165 antibody, AA959768 antibody, CcOX antibody, cytochrome c oxidase subunit 5A antibody, Cytochrome c oxidase subunit 5A antibody, cytochrome c oxidase subunit Vab antibody, cytochrome c oxidase subunit 5A, mitochondrial antibody, cytochrome c oxidase subunit Va S homeolog antibody, cytochrome c oxidase subunit Va antibody, cytochrome C oxidase subunit Va antibody, cytochrome c oxidase subunit Vaa antibody, COX5A antibody, cox5ab antibody, LOC408837 antibody, cox5a.S antibody, cox5a antibody, Cox5a antibody, CoVa antibody, AFUA_5G02750 antibody, IscW_ISCW008682 antibody, LOC100134927 antibody, cox5aa antibody, LOC100988094 antibody
背景
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.