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alpha KGDHC 抗体

alphaKGDHC 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7011083
发货至: 中国
  • 抗原 See all alpha KGDHC (alphaKGDHC) 抗体
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    适用
    • 26
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 25
    • 1
    克隆类型
    • 25
    • 1
    多克隆
    标记
    • 15
    • 3
    • 3
    • 3
    • 1
    • 1
    This alpha KGDHC antibody is un-conjugated
    应用范围
    • 22
    • 14
    • 14
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human OGDH (NP_001003941.1).
    亚型
    IgG
    Top Product
    Discover our top product alphaKGDHC Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    alpha KGDHC (alphaKGDHC) (alpha Ketoglutarate Dehydrogenase (alphaKGDHC))
    别名
    OGDH (alphaKGDHC 产品)
    背景
    This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    分子量

    Observed_MW: 116 kDa

    Calculated_MW: 48 kDa/115 kDa

    基因ID
    4967
    UniProt
    Q02218
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